Formula: C20H19FINO Molecular Weight: 435.3 Pharmacological Drug Class: AM-694 is a potent synthetic cannabinoid (CB) that primarily acts as_x000D_ a selective agonist for the cannabinoid receptor CB1 (Ki = 0.08 nM) (1).It also has affinity for CB2_x000D_ with a Ki value of 1.44 nM. Additionally, the EC50 and CB1 Emax (%) were reported as 52.8 nM and_x000D_ 63%, respectively with GTP binding assays (2). Metabolism: Little is known about the metabolism of AM-694 in humans. GC-MS analysis of human urine samples after self-administration experiments identified six metabolites and no parent compound (3). Metabolites were hypothesized to be formed by 1) hydrolytic defluorination, 2)_x000D_ carboxylation, 3) monohydroxylation of N-alkyl chain, and 4) hydrolytic defluorination combined with monohydroxylation of N-alkyl chain. Major metabolites were hydrolytically defluorinated and carboxylated products. The hydrolytic defluorination metabolite also was identified in urine samples

Buy AM-694 Online It is used in scientific research for mapping the distribution of CB1 receptors.

from two individuals admitted to the hospital for suspected drug overdose. Blood Concentrations: Hermanns-Clausen et al. performed a retrospective study on patients seeking emergency treatment for synthetic cannabinoids (4). Authors quantified AM-694 in serum (0.20 µg/L) in only one patient. JWH-122 also was detected in this patient (9 µg/L). AM-694 also was detected in post mortem femoral blood (0.00009 µg/g) in combination with other synthetic cannabinoids and methoxetamine.

Full Chemical Name: AM 694 Online  Systematic IUPAC Name: 1-[(5-fluoropentyl)-1H- indol-3-yl]-(2- iodophenyl)methanone CAS Number: 335161-03-0 ChemSpider Number: 80648438064843 Molecular Formula: C20H19FINO_ Molecular Mass: 435.273 g/mol